Description: Scheme electron microscopy.
A myeloblast is a large cell (10-20 mm) with a large nucleus (fine disperse chromatin) and nucleolus. In the cytoplasm the Golgi area is well developed, few large mitochondria and rough endoplasmic reticulum profiles with numerous free ribosomes and polysomes are shown and very few electron-dense granules might be present.
Background: The myeloblast originates from a promyeloblast which in turn is derived from CFU-S (colony forming units-spleen) stem cells and subsequently CFU-GM (colony forming unit-granulocyte/monocyte) stem cells. Myeloblasts are the precursor cells for the promyelocytes, myelocytes followed by the granulocytes.
Keywords/Mesh: blood, bone marrow, myeloblast, histology, electron microscopy, POJA collection