Title: Multiple myeloma, plasma cell leukemia in bone marrow smear (human)
Description: Stain: May-Grünwald-Giemsa (MGG).
Multiple myeloma (Kahler’s disease) is characterized by proliferation of abnormal plasma cells (1, myeloma cells) in the bone marrow. In the great majority of patients secretion of a single homogenous immunoglobulin product (monoclonal component) occurs. Note the eccentric location of the nucleus in the plasma cell, and the clear juxtanuclear light zone (Golgi area).
(3): Binucleate plasma cell.
Keywords/Mesh: blood, bone marrow, plasma cell, Kahler’s disease, multiple myeloma, histology, POJA collection