Title: Endometrioid adenocarcinoma, well-differentiated (human, adult)
Description: Stain: (A) Hematoxylin-eosin; (B) CK 7 (OVTL 12-30) antikeratin antibody immunoperoxidase staining with diaminobenzidin reaction (DAB) (B).
(A): Variation in form, and size of the glandular structure of the tumor (1) as well as irregular arrangement of the glandular epithelia. Stroma (2) with dispersed chronic inflammatory cells.
(B): Slight heterogeneity in CK 7 expression (brown-stained) of the glandular lining. Mitoses and polymorphism of cells/nuclei are present. Stroma (2) negative, note ‘back-to-back’ glands (*) representing non-destructive replacement of endometrial stroma by tumor. (Partly by courtesy of G. P. Vooijs MD PhD, former Head of the Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands).
Keywords/Mesh: female reproductive organs, uterus, endometrioid adenocarcinoma, endometrial neoplasms, adenocarcinoma, keratin 7, histology, POJA collection.