Title: Epithelial lining of terminal bronchiole
Electron microscopy, golden hamster. Two major epithelial cell types line the bronchiolus: (1) the ciliated cells with many organelles, and (2) the non-ciliated cells or Clara cells well provided with organelles, especially agranular endoplasmic reticulum and depending on their activity numerous electron-dense secretory granules (hardly present in this picture). On the basal lamina a N(euro)E(pithelial)B(ody) composed of a cluster of small neuroendocrine cells (3) (belonging to the Amine Precursor Uptake and Decarboxylation cell system so-called APUD cells). The dense-core granules contain among others dopamine or serotonin.
Great alveolar cells (so-called pneumocyte II) are represented at (4); interstitium with elastin/collagen/myofibroblasts is found around (5), while (6) represents the alveolar space.
Title: Neuroepithelial body in terminal bronchiole
Electron microscopy, golden hamster. Three epithelial cells, as part of N(euro)E(pithelial)B(ody), contribute to a cluster of neuro-endocrine cells. They belong to the Amine Precursor Uptake and Decarboxylation cell system so-called APUD cells. The dense-core granules (↓) contain among others dopamine or serotonin and are preferentially localized together with mitochondria (*) in the basal compartment below the nucleus.
Keywords/Mesh: respiratory tract, lung, terminal bronchiole,
(neuro)endocrine cell, APUD cell, neuroepithelial body, ciliated epithelium, Clara cell, alveolus, alveolar cell, pneumocyte, interstitium, histology, electron microscopy, POJA collection