10.3 POJA-L2256+2257+
2255+2247+2248+2259.
Tissue mast cells (dermis of skin)
10.3 POJA-L2256+2257+2255+2247+2248+2259
Title: Tissue mast cells (dermis of skin)
Description:
(A): Arm skin, stain PAS, human. The intensely stained pink cells due to their content of glycoproteins are tissue mast cells
embedded in the connective tissue. Similar with (B) and (C).
(B): Peritoneum, stain toluidine blue, rat. The mast cells contain vasoactive granules (metachromasia). Similar with (C).
(C): Peritoneum, stain trichrome-light green, human. Granulated mast cells at higher magnification. Similar with (B).
(D-F): Arm skin, electron microscopy, human. Mast cell (D, F) with granules. In (D) parallel to the mast cell part of
a fibroblast containing intermediate 10 nm filaments (vimentin). Granules may display different internal structures
as shown here with characteristic ‘scroll’ and crystalline formations, detailed in (F).
Background: The vasoactive content of the granules includes chemotactic mediators, proteases, proteoglycans,
histamine, heparin. Note that the enzyme tryptase is present in mast cells of mucosal and connective tissue
but not in basophilic granulocytes despite their common progenitor cells within the bone marrow.
Keywords/Mesh: skin, dermis, connective tissue, mast cell, metachromasia, histology, electron microscopy, POJA collection
Title: Tissue mast cells (dermis of skin)
Description:
(A): Arm skin, stain PAS, human. The intensely stained pink cells due to their content of glycoproteins are tissue mast cells
embedded in the connective tissue. Similar with (B) and (C).
(B): Peritoneum, stain toluidine blue, rat. The mast cells contain vasoactive granules (metachromasia). Similar with (C).
(C): Peritoneum, stain trichrome-light green, human. Granulated mast cells at higher magnification. Similar with (B).
(D-F): Arm skin, electron microscopy, human. Mast cell (D, F) with granules. In (D) parallel to the mast cell part of
a fibroblast containing intermediate 10 nm filaments (vimentin). Granules may display different internal structures
as shown here with characteristic ‘scroll’ and crystalline formations, detailed in (F).
Background: The vasoactive content of the granules includes chemotactic mediators, proteases, proteoglycans,
histamine, heparin. Note that the enzyme tryptase is present in mast cells of mucosal and connective tissue
but not in basophilic granulocytes despite their common progenitor cells within the bone marrow.
Keywords/Mesh: skin, dermis, connective tissue, mast cell, metachromasia, histology, electron microscopy, POJA collection