7.4 POJA-L198+197+235
Title: Mammary gland in pregnancy (human).
Description: Stain: Azan.
(A): Lobule with dilated terminal ductules (acini, alveoli). The lumina contain secretion. Lipid droplets are accumulated in apices of epithelium.
(B): Groups of acini with lipid-rich secretion in lumina. At (1) lumen of interlobular duct.
(C): Higher magnification of peripheral acini in a lobule. Lumen filled with lipid droplets and proteinaceous granular secretion. Apically intracellular lipid vacuoles are present (↓↓).
Background: Milk contains proteins (casein, a-lactalbumin, parathyroid hormone-related proteins), lipids (triglycerides, cholesterol), lactose and IgA (from plasma cells in surrounding stroma of acini). Prolactin stimulates secretion by alveolar cells, oxytocin the contraction of myoepithelial cells. Estrogen promotes branching differentiation, testosteron inhibits. Growth is further affected by epidermal growth factor (receptor), collagen IV, laminin. matrix metalloproteinase, heparan sulfate and other proteoglycans.
Keywords/Mesh: breast, mammary glands, histology, POJA collection, pregnancy, ductules, acini,
Title: Mammary gland in pregnancy (human).
Description: Stain: Azan.
(A): Lobule with dilated terminal ductules (acini, alveoli). The lumina contain secretion. Lipid droplets are accumulated in apices of epithelium.
(B): Groups of acini with lipid-rich secretion in lumina. At (1) lumen of interlobular duct.
(C): Higher magnification of peripheral acini in a lobule. Lumen filled with lipid droplets and proteinaceous granular secretion. Apically intracellular lipid vacuoles are present (↓↓).
Background: Milk contains proteins (casein, a-lactalbumin, parathyroid hormone-related proteins), lipids (triglycerides, cholesterol), lactose and IgA (from plasma cells in surrounding stroma of acini). Prolactin stimulates secretion by alveolar cells, oxytocin the contraction of myoepithelial cells. Estrogen promotes branching differentiation, testosteron inhibits. Growth is further affected by epidermal growth factor (receptor), collagen IV, laminin. matrix metalloproteinase, heparan sulfate and other proteoglycans.
Keywords/Mesh: breast, mammary glands, histology, POJA collection, pregnancy, ductules, acini,