Title: Fibrin phagocytosis by neutrophils (peripheral blood, mouse)
Description: Electron microscopy.
At site of tissue damage motile neutrophils are among the first to be involved actively in phagocytosis. In between a cluster of neutrophilic granulocytes fibrin depositions (1) are present.
At (1→) fibrin accumulations are close attached to the surface of a neutrophil indicating the beginning of phagocytosis. The cytoplasm of all neutrophils changes, showing granule-depleted areas (degranulation effect) as the granules discard their contents.
There is a loss of glycogen, presence of fat droplets (3) and the formation of large electron-light vacuoles (4).
(5): Indicates nuclear lobes and nuclear strands.
(6) : Neutrophilic granules.
(2): Swollen mitochondria and endoplasmic reticulum.
Keywords/Mesh: blood, bone marrow, neutrophilic granulocyte, phagocytosis, histology, electron microscopy, POJA collection