7.1 POJA-L1217+1563+1235. Tertiary (antral) follicles in ovary (human, rabbit)
7.1 POJA-L1217+1563+1235
Title: Tertiary (antral) follicles in ovary (human, rabbit)
Description: Scheme (human, A). Stain: (B) Trichrome (Goldner) (human), (C) Azan (rabbit). Note: the individual magnifications in this photomontage are irrelevant.
(A): Scheme (human): large antral follicle (tertiary follicle type 5+) becomes a mature or preovulatory (Graafian) follicle. Antrum folliculi with liquor folliculi (1); cumulus with oocyte (2); mural granulosa cells (3); internal theca with differentiation of stromal cells into spindle-shaped cells (4); external theca with more fibrous components (collagen) (5).
(B): Human: tertiary follicle type 5 (antral stage) and antrum (1). Cumulus (2) with oocyte (no nucleus sectioned) and a thick green-stained zona pellucida (→). Mural granulosa cells (3); internal theca with blood vessels (4); external theca with more fibrous components (collagen) (5).
(C): Rabbit: tertiary follicle type 5 (antral stage) and antrum. Cumulus with oocyte and vesicular nucleus/nucleolus. A bluish-stained zona pellucida with corona radiata (ring of granulosa cells surrounding oocyte. Mural granulosa cells; internal theca cells; external theca with blue-stained collagen fibers. Remnants of atretic follicles at (6) and interstitial cells at (7).
Background: Tertiary follicles are antral follicles with multiple layers of mural granulosa cells. Type 5 follicle has more than five layers of granulosa cell layers and a large antrum.
Type 5+ follicle becomes a mature or preovulatory (Graafian) follicle with a size up to 20 mm. In rabbit ovary granulosa cells of many atretic follicles degenerate completely and transform into a lipid mass that is phagocytized. Meanwhile enlarged epithelioid theca cells becoming ‘luteinized’ with lipid inclusions in a glandular arrangement. They give rise to the glandular cell masses which contribute to the bulk of interstitial tissue in adult ovaries. But later on thecal cells actively develop into lipid-containing glandular interstitial cells and the process continues as follicles become atretic throughout life.
Keywords/Mesh: female genitalia, ovary, antral ovarian follicle, tertiary follicle, Graafian follicle, granulosa cells, theca cells, histology, POOJA collection
Title: Tertiary (antral) follicles in ovary (human, rabbit)
Description: Scheme (human, A). Stain: (B) Trichrome (Goldner) (human), (C) Azan (rabbit). Note: the individual magnifications in this photomontage are irrelevant.
(A): Scheme (human): large antral follicle (tertiary follicle type 5+) becomes a mature or preovulatory (Graafian) follicle. Antrum folliculi with liquor folliculi (1); cumulus with oocyte (2); mural granulosa cells (3); internal theca with differentiation of stromal cells into spindle-shaped cells (4); external theca with more fibrous components (collagen) (5).
(B): Human: tertiary follicle type 5 (antral stage) and antrum (1). Cumulus (2) with oocyte (no nucleus sectioned) and a thick green-stained zona pellucida (→). Mural granulosa cells (3); internal theca with blood vessels (4); external theca with more fibrous components (collagen) (5).
(C): Rabbit: tertiary follicle type 5 (antral stage) and antrum. Cumulus with oocyte and vesicular nucleus/nucleolus. A bluish-stained zona pellucida with corona radiata (ring of granulosa cells surrounding oocyte. Mural granulosa cells; internal theca cells; external theca with blue-stained collagen fibers. Remnants of atretic follicles at (6) and interstitial cells at (7).
Background: Tertiary follicles are antral follicles with multiple layers of mural granulosa cells. Type 5 follicle has more than five layers of granulosa cell layers and a large antrum.
Type 5+ follicle becomes a mature or preovulatory (Graafian) follicle with a size up to 20 mm. In rabbit ovary granulosa cells of many atretic follicles degenerate completely and transform into a lipid mass that is phagocytized. Meanwhile enlarged epithelioid theca cells becoming ‘luteinized’ with lipid inclusions in a glandular arrangement. They give rise to the glandular cell masses which contribute to the bulk of interstitial tissue in adult ovaries. But later on thecal cells actively develop into lipid-containing glandular interstitial cells and the process continues as follicles become atretic throughout life.
Keywords/Mesh: female genitalia, ovary, antral ovarian follicle, tertiary follicle, Graafian follicle, granulosa cells, theca cells, histology, POOJA collection