5.7 POJA-L2521+La0092+2430+La0081
Title: Umbrella cells in the urothelium of the urinary bladder II
Description:
(A): Urothelium, electron microscopy scheme, human.
(B): Scanning electron micrograph of the superficial epithelial cells or umbrella cells, human. Numerous scallop-shaped membrane
plaques cover most apical surfaces of intact facet cells (green arrows).
(C, D): Urothelium, electron microscopy, rat resp. gerbil. Superficial urothelial cells or facet cells with numerous fusiform or discoid
vesicles containing uroplakins and plasma membrane fragments.
The fusiform/discoid vesicles function as transporting compartments to deliver urothelial plaques to the apical cell membrane (blue arrows).
Background: Uroplakins are transmembrane proteins that act a barrier to a.o. water, small non-electrolytes.
Facet cell contain fusiform or discoid vesicles containing the plaques composed of asymmetrically thickened membrane domains (AUMs). An AUM consists of the assembly of four uroplakins i.e. Ia, Ib, II and III. The uroplakins are involved in the homeostasis in the urinary bladder mucosa and prevent the AUMs from rupturing during bladder contraction and relaxation.
Keywords/Mesh: urinary system, urinay bladder, vesica urinaria, urothelium, transitional epithelium, umbrella cell, facet cell, uroplakin, histology, electron microscopy, POJA collection
Title: Umbrella cells in the urothelium of the urinary bladder II
Description:
(A): Urothelium, electron microscopy scheme, human.
(B): Scanning electron micrograph of the superficial epithelial cells or umbrella cells, human. Numerous scallop-shaped membrane
plaques cover most apical surfaces of intact facet cells (green arrows).
(C, D): Urothelium, electron microscopy, rat resp. gerbil. Superficial urothelial cells or facet cells with numerous fusiform or discoid
vesicles containing uroplakins and plasma membrane fragments.
The fusiform/discoid vesicles function as transporting compartments to deliver urothelial plaques to the apical cell membrane (blue arrows).
Background: Uroplakins are transmembrane proteins that act a barrier to a.o. water, small non-electrolytes.
Facet cell contain fusiform or discoid vesicles containing the plaques composed of asymmetrically thickened membrane domains (AUMs). An AUM consists of the assembly of four uroplakins i.e. Ia, Ib, II and III. The uroplakins are involved in the homeostasis in the urinary bladder mucosa and prevent the AUMs from rupturing during bladder contraction and relaxation.
Keywords/Mesh: urinary system, urinay bladder, vesica urinaria, urothelium, transitional epithelium, umbrella cell, facet cell, uroplakin, histology, electron microscopy, POJA collection