Title: Phagocytosis of latex by neutrophil (peripheral blood, human)
Description: Electron microscopy.
The primary function of neutrophilic granulocytes is phagocytosis, ingestion of and destroying microbes or, as shown here, of latex particles.
(1): Several electron-light latex particles (1) (with a dense core) are internalized after incubation of free circulating granulocytes with a latex suspension.
(2): Nuclear lobes.
(3): Few blunt filopodia .
There are still abundant primary and secondary granules (4), there is no direct evidence of a degranulation effect as latex particles will be individually internalized but appear very difficult to be degraded by these phagocytes.
At (5) a large phagolysosome in which five latex particles are collected.
(6): Indicates free circulating latex particles.
Keywords/Mesh: blood, bone marrow, neutrophilic granulocyte, lysosome, phagocytosis, histology, electron microscopy, POJA collection