1.1 POJA-L769. Phagocytosis of latex by neutrophil (peripheral blood, human

return to blood & bone marrow images

1.1  POJA-L769

Title: Phagocytosis of latex by neutrophil (peripheral blood, human)
 
Description: Electron microscopy.

​The primary function of neutrophilic granulocytes is phagocytosis, ingestion of and destroying microbes or, as shown here, of latex particles.
(1): Several electron-light latex particles (1) (with a dense core) are internalized after incubation of free circulating granulocytes with a latex suspension.
(2): Nuclear lobes.
​(3): Few blunt filopodia .

There are still abundant primary and secondary granules (4), there is no direct evidence of a degranulation effect as latex particles will be individually internalized but appear very difficult to be degraded by these phagocytes.

At (5) a large phagolysosome in which five latex particles are collected.

(6): Indicates free circulating latex particles.
 
Keywords/Mesh: blood, bone marrow, neutrophilic  granulocyte, lysosome, phagocytosis, histology,  electron microscopy, POJA collection