9.7 POJA-L2990+2991.
Neuroendocrine cells (I) in the principal bronchus of the golden hamster lung
9.7 POJA-L2990+2991
Title: Neuroendocrine cells (I) in the principal bronchus of the golden hamster lung
Description:
(A, B): Brochus, electron micrographs of single neuroendocrine cells. Intraepithelial neuroendocrine cell (A, 1) with electron-dense granules and few larger and dense lysosomes. (A, 2) Lining non-ciliated cell of the bronchus. (A, 3) Lumen of the bronchus.
Background: Neuroendocrine cell with granules or so-called Kultschitsky type cells are also found within the lining respiratory
mucosa, they are classified as APUD cells (Amine Precursor Uptake Decarboxylation). The neuroendocrine cells or neurosecretory cells release their hormone content upon stimulation by nerve cells as also shown in the medulla of the adrenal gland.
These pulmonary neuroendocrine cells (PNEC) are specialized solitary epithelial cells sometimes arranged in clusters called neuroepithelial bodies (NEB) in the lung. These bodies appear as oygen-sensitive chemoreceptors. The cells can contain hormones such as serotonin, calcitonin, chromogranin, gastrin releasing peptide (GRP) and cholecystokinin.
Keywords/Mesh: adrenal gland, lung, bronchus, neuroendocrine cell, chemoreceptor, histology, electron microscopy, POJA collection
Title: Neuroendocrine cells (I) in the principal bronchus of the golden hamster lung
Description:
(A, B): Brochus, electron micrographs of single neuroendocrine cells. Intraepithelial neuroendocrine cell (A, 1) with electron-dense granules and few larger and dense lysosomes. (A, 2) Lining non-ciliated cell of the bronchus. (A, 3) Lumen of the bronchus.
Background: Neuroendocrine cell with granules or so-called Kultschitsky type cells are also found within the lining respiratory
mucosa, they are classified as APUD cells (Amine Precursor Uptake Decarboxylation). The neuroendocrine cells or neurosecretory cells release their hormone content upon stimulation by nerve cells as also shown in the medulla of the adrenal gland.
These pulmonary neuroendocrine cells (PNEC) are specialized solitary epithelial cells sometimes arranged in clusters called neuroepithelial bodies (NEB) in the lung. These bodies appear as oygen-sensitive chemoreceptors. The cells can contain hormones such as serotonin, calcitonin, chromogranin, gastrin releasing peptide (GRP) and cholecystokinin.
Keywords/Mesh: adrenal gland, lung, bronchus, neuroendocrine cell, chemoreceptor, histology, electron microscopy, POJA collection