9.9 POJA-L3862+3863+3865
+3864.
Medullary thyroid carcinoma
9.9 POJA-L3862+3863+3865+3864
Title: Medullary thyroid carcinoma
Description:
Stained semi-consecutive sections of tumor.
(A): Congo red stains the normal follicle content (1) positively, but leaves the thyroid carcinoma cells (2) negative, human.
(B): Immunoperoxidase-DAB staining with antithyroglobulin antibodies shows that the content of the normal thyroid follicles are
stained positively, but leaves the carcinoma part (2) unstained.
(C): Immunoperoxidase-DAB-staining with antibodies to calcitonin. The normal follicles (1) are negative, but several tumor clusters (3)
are stained positively, few are negative (2).
(D): Immunoperoxidase staining with DAB and antibodies against CEA (Carcinoembryonic antigen). The normal follicles are negative (1) while the papilliferous adenocarcinoma cells (2) are positive.
The medullary thyroid cancer originates from the parafollicular cells or C-cells which produce calcitonin.
The follicles are negative, the tumor cells are positive (2).
The medullary thyroid cancer is a neuroendocrine tumor that originates from the parafollicular cells or C-cells which produce calcitonin. The diagnosis is partly based on the use of the monoclonal antibodies against calcitonin and CEA.
Keywords/Mesh: thyroid gland, medullary thyroid cancer, calcitonin, histology, pathology, POJA collection
Title: Medullary thyroid carcinoma
Description:
Stained semi-consecutive sections of tumor.
(A): Congo red stains the normal follicle content (1) positively, but leaves the thyroid carcinoma cells (2) negative, human.
(B): Immunoperoxidase-DAB staining with antithyroglobulin antibodies shows that the content of the normal thyroid follicles are
stained positively, but leaves the carcinoma part (2) unstained.
(C): Immunoperoxidase-DAB-staining with antibodies to calcitonin. The normal follicles (1) are negative, but several tumor clusters (3)
are stained positively, few are negative (2).
(D): Immunoperoxidase staining with DAB and antibodies against CEA (Carcinoembryonic antigen). The normal follicles are negative (1) while the papilliferous adenocarcinoma cells (2) are positive.
The medullary thyroid cancer originates from the parafollicular cells or C-cells which produce calcitonin.
The follicles are negative, the tumor cells are positive (2).
The medullary thyroid cancer is a neuroendocrine tumor that originates from the parafollicular cells or C-cells which produce calcitonin. The diagnosis is partly based on the use of the monoclonal antibodies against calcitonin and CEA.
Keywords/Mesh: thyroid gland, medullary thyroid cancer, calcitonin, histology, pathology, POJA collection