POJA-L1643+1943+103. Mammary gland in pregnancy (human)
POJA-L1643+1943+103
Title: Mammary gland in pregnancy (human)
Description: Stain: (A) Azan; (B) Black/white image of hematoxylin-eosin; (C) Scheme electron microscopy.
(A): Lobule with dilated terminal ductules (acini, alveoli). The lumina contain secretion. Lipid droplets in apices of epithelium.
(B): High magnification of part of two acini (alveoli). Different types of intracellular secretion vacuoles are present as dark dots and globules. Myoepithelial cells (arrows).
(C): Glandular epithelial cell (1) and myoepithelial cell (2) with myofilaments surrounded by a basal lamina (arrow). Epithelial cells are junctioned and may form an intercellular canaliculus. (3). Electron-dense droplets of various sizes represent lipid secretion in an apocrine way. Minute accumulations of proteins will be secreted via a merocrine way.
Background: Myoepithelial cells are 10-20 times more sensitive to oxytocin than myometrial smooth muscle cells. Contraction of myoepithelial cells contributes to the ejection of milk. Milk contains proteins (casein, a-lactalbumin and parathyroid hormone-related proteins), lipids (triglycerides, cholesterol), lactose and IgA (from plasma cells in surrounding stroma of acini). Prolactin stimulates secretion by alveolar cells.
Keywords/Mesh: breast, mammary glands, histology, POJA collection, pregnancy, myoepithelial cells,
Title: Mammary gland in pregnancy (human)
Description: Stain: (A) Azan; (B) Black/white image of hematoxylin-eosin; (C) Scheme electron microscopy.
(A): Lobule with dilated terminal ductules (acini, alveoli). The lumina contain secretion. Lipid droplets in apices of epithelium.
(B): High magnification of part of two acini (alveoli). Different types of intracellular secretion vacuoles are present as dark dots and globules. Myoepithelial cells (arrows).
(C): Glandular epithelial cell (1) and myoepithelial cell (2) with myofilaments surrounded by a basal lamina (arrow). Epithelial cells are junctioned and may form an intercellular canaliculus. (3). Electron-dense droplets of various sizes represent lipid secretion in an apocrine way. Minute accumulations of proteins will be secreted via a merocrine way.
Background: Myoepithelial cells are 10-20 times more sensitive to oxytocin than myometrial smooth muscle cells. Contraction of myoepithelial cells contributes to the ejection of milk. Milk contains proteins (casein, a-lactalbumin and parathyroid hormone-related proteins), lipids (triglycerides, cholesterol), lactose and IgA (from plasma cells in surrounding stroma of acini). Prolactin stimulates secretion by alveolar cells.
Keywords/Mesh: breast, mammary glands, histology, POJA collection, pregnancy, myoepithelial cells,