POJA-L 1675+1877+1585
Title: Endometriosis, colorectal (human, adult)
Description: Stain: (A, B) Hematoxylin-eosin.
(A): Survey. Endometriotic glands (1) expanding from submucosal region to proper lamina and up to tip of the mucosa of the colon. Crypts of colorectal area (2) with single lymphatic aggregation and muscularis mucosae (3).
(B): Submucosal endometriotic glands (1) embedded in hemorrhagic endometrial stroma (4), muscularis mucosae (3) and proper lamina with deep crypts (2).
(C): Blood-filled cyst (5) with lining glandular epithelium, endometriotic glands (1) within stroma (4), external muscularis (6). (Partly by courtesy of G.P. Vooijs MD PhD, former Head of the Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands).
Clinical background: The most common site of extrapelvic endometriosis (5-15%) is the gastrointestinal tract. In colonic endometriosis sigmoid colon and rectum are the most involved areas (75-90%). Invasion of endometriosis is also observed in upper rectum and sigmoid colon by contiguous spreading even infiltrating the muscularis. Cyclical rectal bleeding (hematochezia) is pathognomic of endometriosis.
Keywords/Mesh: female reproductive organs, extrapelvic endometriosis, endometriosis, colonic endometriosis, histology, POJA collection.
Title: Endometriosis, colorectal (human, adult)
Description: Stain: (A, B) Hematoxylin-eosin.
(A): Survey. Endometriotic glands (1) expanding from submucosal region to proper lamina and up to tip of the mucosa of the colon. Crypts of colorectal area (2) with single lymphatic aggregation and muscularis mucosae (3).
(B): Submucosal endometriotic glands (1) embedded in hemorrhagic endometrial stroma (4), muscularis mucosae (3) and proper lamina with deep crypts (2).
(C): Blood-filled cyst (5) with lining glandular epithelium, endometriotic glands (1) within stroma (4), external muscularis (6). (Partly by courtesy of G.P. Vooijs MD PhD, former Head of the Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands).
Clinical background: The most common site of extrapelvic endometriosis (5-15%) is the gastrointestinal tract. In colonic endometriosis sigmoid colon and rectum are the most involved areas (75-90%). Invasion of endometriosis is also observed in upper rectum and sigmoid colon by contiguous spreading even infiltrating the muscularis. Cyclical rectal bleeding (hematochezia) is pathognomic of endometriosis.
Keywords/Mesh: female reproductive organs, extrapelvic endometriosis, endometriosis, colonic endometriosis, histology, POJA collection.