Description: Scheme electron microscopy.
The lymphoblast shows a high nucleus-cytoplasm ratio, it is a large cell (10-20 mm) with a large nucleus and distinct nucleolus. Apart from numerous ribosomes, a small juxtanuclear Golgi area the cyoplasm is scanty with very few organelles.
Background: A pluripotent hematopoietic stem cell gives rise to a common lymphoid progenitor cell. The latter divides to produce two types of lymphoid stem cells. One type migrates to the thymus, proliferates and differentiates into T lymphocytes. The other type remains in the bone marrow or settles in the spleen, lymph nodes where it proliferates into lymphoblasts that in turn divide and eventually result in immunocompetent B lymphocytes. Dependent on the appropriate stimulation the latter cells might differentiate via plasmablasts into plasma cells.
Keywords/Mesh: blood, bone marrow, lymphoblast, histology, electron microscopy, POJA collection