7.2 POJA-L1545+1872. Endometrioid adenocarcinoma, well-differentiated (uterus, human, adult)
7.2 POJA-L1545+1872
Title: Endometrioid adenocarcinoma, well-differentiated (uterus, human, adult)
Description: Stain: (A, B) Hematoxylin-eosin.
(A): Survey of exophytic tumor (2) in endometrial cavity (1).
(B): Variety of glandular formations in diameter and form, stroma with focally accumulation of chronic inflammation cells (3).
(By courtesy of G. P. Vooijs MD PhD, former Head of the Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands).
Clinical background: Endometrial carcinoma. The average mean age of occurrency is about 55 years, and among them ca. 75% postmenopausal, 20% premenopausal and 5% before 40 years. Generally of all tumors 95 % are adenocarcinomas and 5% are classified as squamous carcinomas. Usually two types of carcinomas are distinguished:
Keywords/Mesh: endometrial carcinoma, female reproductive organs, endometrium cancer, endometrioid carcinoma, endometrium, uterus, histology, POJA collection
Title: Endometrioid adenocarcinoma, well-differentiated (uterus, human, adult)
Description: Stain: (A, B) Hematoxylin-eosin.
(A): Survey of exophytic tumor (2) in endometrial cavity (1).
(B): Variety of glandular formations in diameter and form, stroma with focally accumulation of chronic inflammation cells (3).
(By courtesy of G. P. Vooijs MD PhD, former Head of the Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands).
Clinical background: Endometrial carcinoma. The average mean age of occurrency is about 55 years, and among them ca. 75% postmenopausal, 20% premenopausal and 5% before 40 years. Generally of all tumors 95 % are adenocarcinomas and 5% are classified as squamous carcinomas. Usually two types of carcinomas are distinguished:
- Type I endometrial cancer which has endometrioid histology (low-grade endometrioid type) and is minimally invasive in the uterine wall (good prognosis). It is more common in premenopausal women, associated with chronic estrogen exposure and is often preceded by premalignant lesion (e.g. endometrial hyperplasia).
- Type II endometrial cancer is estrogen-independent with nonendometrioid histology (high-grade endometrioid type i.e.with increasing dedifferentiation resulting in papillary serous carcinoma or clear cell carcinoma). It is common in older postmenopausal women. The prognosis is poorer due to the aggressive clinical course.
Keywords/Mesh: endometrial carcinoma, female reproductive organs, endometrium cancer, endometrioid carcinoma, endometrium, uterus, histology, POJA collection