7.1 POJA-L1746+1739
Title: Corpus fibrosa and small corpus albicans in ovary (human)
Description: Stain: (A) Trichrome (Goldner); (B) Hematoxylin-eosin.
(A): Corpus fibrosum (or corpus atreticum), a small scar consisting of tortuous hyaline tissue (1) surrounded by cell-rich ovarian stroma and many thin-walled blood vessels. At (2) border of large follicle antrum with lining of granulosa cells.
(B): Ovarian medulla with corpus albicans (1) derived from a corpus luteum spurium (corpus luteum of menstruation). The hyalinized scar contains relatively acellular collagenous tissue and is embedded within fibrous ovarian stroma with larger blood vessels.
Background: A corpus luteum of menstruation (corpus luteum cyclicum, spurium) may exist for about 2 weeks if no fertilization of the ovum takes place. After luteolysis (involution of corpus luteum) a cascade of apoptosis, fatty degeneration of lutein cells, autolysis and removal by macrophages follows. Gradually a small fibrous hyaline-like scar is left after about two months (small corpus albicans). Not all follicles develop fully; many are lost at various stages of development due to the process of atresia. If atresia occurs at an early stage the follicles e.g. primary follicles completely disappear, but if the process occurs at a later stage e.g. secondary follicles, antral follicles the oocyte degenerates. Due to collapse of the antrum the basement membrane (membrane vitrea) between granulosa cells and theca interna layers transforms into a thick, wavy and hyalinized band the so-called glassy membrane. Surrounded by proliferating connective tissue small fibrotic scars (corpora fibrosa or corpora atretica) or even small cysts are the results. With exception of persisting larger corpora albicantia (from corpus luteum of pregnancy) gradually all other smaller corpora albicantia and corpora atretica (or fibrosa) are pushed towards the medulla and merge with the ovarian stroma.
Keywords/Mesh: female reproductive organs, ovary, corpus luteum, corpus albicans, corpus atreticum, granulosa cells, histology, POJA collection
Title: Corpus fibrosa and small corpus albicans in ovary (human)
Description: Stain: (A) Trichrome (Goldner); (B) Hematoxylin-eosin.
(A): Corpus fibrosum (or corpus atreticum), a small scar consisting of tortuous hyaline tissue (1) surrounded by cell-rich ovarian stroma and many thin-walled blood vessels. At (2) border of large follicle antrum with lining of granulosa cells.
(B): Ovarian medulla with corpus albicans (1) derived from a corpus luteum spurium (corpus luteum of menstruation). The hyalinized scar contains relatively acellular collagenous tissue and is embedded within fibrous ovarian stroma with larger blood vessels.
Background: A corpus luteum of menstruation (corpus luteum cyclicum, spurium) may exist for about 2 weeks if no fertilization of the ovum takes place. After luteolysis (involution of corpus luteum) a cascade of apoptosis, fatty degeneration of lutein cells, autolysis and removal by macrophages follows. Gradually a small fibrous hyaline-like scar is left after about two months (small corpus albicans). Not all follicles develop fully; many are lost at various stages of development due to the process of atresia. If atresia occurs at an early stage the follicles e.g. primary follicles completely disappear, but if the process occurs at a later stage e.g. secondary follicles, antral follicles the oocyte degenerates. Due to collapse of the antrum the basement membrane (membrane vitrea) between granulosa cells and theca interna layers transforms into a thick, wavy and hyalinized band the so-called glassy membrane. Surrounded by proliferating connective tissue small fibrotic scars (corpora fibrosa or corpora atretica) or even small cysts are the results. With exception of persisting larger corpora albicantia (from corpus luteum of pregnancy) gradually all other smaller corpora albicantia and corpora atretica (or fibrosa) are pushed towards the medulla and merge with the ovarian stroma.
Keywords/Mesh: female reproductive organs, ovary, corpus luteum, corpus albicans, corpus atreticum, granulosa cells, histology, POJA collection