4.1.1 POJA-La0327+La0163+La0328+L4002
Title: Duodenum (human)
Description: Stain: Azan.
(A) The survey of the duodenum shows three plicae circulares or Kerckring’s folds serving as surface amplification of the duodenum. The folds comprise both the mucosa and submucosa layer, but not the tunica muscularis and serosa.
(A, 1) Outer longitudinal muscle layer.
(A, 2) Inner circular muscle layer.
(A, 3) Submucosa.
(A, 4) Lieberkühn crypts and Brunner glands.
Further surface amplification is realized by folding of the surface mucosa into villi (B, 5) and crypts (B, 6), detailed in (C).
The duodenal glands (D, 4) end in the bottom of the crypts (D, 5), where also goblet cells (stained blue) are present.
Arrow (D, ↘) points to mitosis in the lower part of a crypt.
The duodenal glands produce a mucus-rich alkaline secretion (MUC6 and bicarbonate) used to neutralize the acid content of the stomach, thus providing the optimal conditions for the further enzymatic digestion of the food. They also secrete urogastrone which inhibits parietal cells and chief cells of the stomach.
Keywords/Mesh: duodenum, Brunner glands, plicae of Kerckring, histology, POJA collection
Title: Duodenum (human)
Description: Stain: Azan.
(A) The survey of the duodenum shows three plicae circulares or Kerckring’s folds serving as surface amplification of the duodenum. The folds comprise both the mucosa and submucosa layer, but not the tunica muscularis and serosa.
(A, 1) Outer longitudinal muscle layer.
(A, 2) Inner circular muscle layer.
(A, 3) Submucosa.
(A, 4) Lieberkühn crypts and Brunner glands.
Further surface amplification is realized by folding of the surface mucosa into villi (B, 5) and crypts (B, 6), detailed in (C).
The duodenal glands (D, 4) end in the bottom of the crypts (D, 5), where also goblet cells (stained blue) are present.
Arrow (D, ↘) points to mitosis in the lower part of a crypt.
The duodenal glands produce a mucus-rich alkaline secretion (MUC6 and bicarbonate) used to neutralize the acid content of the stomach, thus providing the optimal conditions for the further enzymatic digestion of the food. They also secrete urogastrone which inhibits parietal cells and chief cells of the stomach.
Keywords/Mesh: duodenum, Brunner glands, plicae of Kerckring, histology, POJA collection