13.1 POJA-L-4642+La0301+4721+4626+4625 Capillaries: inner and outer lining cells
13.1 POJA-L4642+La0301+4721+4626+4625
Title: Capillaries: inner and outer lining cells
Description:
(A): Mesenterial vessels and capillaries in mesentery (loose connective tissue) Haematoxylin-Weigert staining, frog.
(B): Idem, detail. The fine fibres in the omentum are elastic, the coarse ones are collagenous. The thin mesenterial capillary is covered with a well visible pericyte (per, green) engulfing the capillary, that is schematically drawn in C1 and C2. Endothelium (end) in (C1).
(D1-D2): show an immunoperoxidase-DAB staining with endothelium marker (G. van Muyen, PhD, Dept. Pathology, Radboudumc) applied on frozen sections of mammary gland tissue (mouse).
Background:
Endothelial cells line the inner surface of blood vessels and lymph vessels. These endothelial cells regulate the exchange of substances between blood and tissues. They form a continuous layer of thin flat cells resembling flattened squamous epithelial cells. The endothelium is involved in:
• Production of anticoagulant and antithrombotic factors e.g. prostacyclin, thrombomodulin, and plasminogen activator.
• Modulation of circulation reactions by production of vasoconstrictors e.g. endothelin, and vasodilatators e.g. prostacyclin, NO.
• Regulation of inflammation and immunity by production of IL-1, IL-6, IL-8, HLA’s, adhesion molecules.
• Regulation of cell growth by production of growth factors e.g. PDGF, CSF, FGF, growth inhibition factors like TGF’s, heparin.
• Oxidation of low density protein.
• Production of prothrombotic factors e.g. v.Willebrand factor, inhibitor plasminogen activator.
• Production of matrix components e.g. collagen IV, laminin, proteoglycans.
Pericytes line the outer surface of blood vessels and stabilise blood vessel walls. They are contractile cells and also regulate capillary blood flow, phagocytosis (Bergers and S Song. The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol 2005 Oct: 7(4):452-464). http://neurooncology.mc.duke.edu;DOI:10.1215/S1152851705000232
Keywords/Mesh: cardiovascular system, vascularisation, blood vessel, mesentery, capillary, endothelium, pericyte, histology, POJA collection
Title: Capillaries: inner and outer lining cells
Description:
(A): Mesenterial vessels and capillaries in mesentery (loose connective tissue) Haematoxylin-Weigert staining, frog.
(B): Idem, detail. The fine fibres in the omentum are elastic, the coarse ones are collagenous. The thin mesenterial capillary is covered with a well visible pericyte (per, green) engulfing the capillary, that is schematically drawn in C1 and C2. Endothelium (end) in (C1).
(D1-D2): show an immunoperoxidase-DAB staining with endothelium marker (G. van Muyen, PhD, Dept. Pathology, Radboudumc) applied on frozen sections of mammary gland tissue (mouse).
Background:
Endothelial cells line the inner surface of blood vessels and lymph vessels. These endothelial cells regulate the exchange of substances between blood and tissues. They form a continuous layer of thin flat cells resembling flattened squamous epithelial cells. The endothelium is involved in:
• Production of anticoagulant and antithrombotic factors e.g. prostacyclin, thrombomodulin, and plasminogen activator.
• Modulation of circulation reactions by production of vasoconstrictors e.g. endothelin, and vasodilatators e.g. prostacyclin, NO.
• Regulation of inflammation and immunity by production of IL-1, IL-6, IL-8, HLA’s, adhesion molecules.
• Regulation of cell growth by production of growth factors e.g. PDGF, CSF, FGF, growth inhibition factors like TGF’s, heparin.
• Oxidation of low density protein.
• Production of prothrombotic factors e.g. v.Willebrand factor, inhibitor plasminogen activator.
• Production of matrix components e.g. collagen IV, laminin, proteoglycans.
Pericytes line the outer surface of blood vessels and stabilise blood vessel walls. They are contractile cells and also regulate capillary blood flow, phagocytosis (Bergers and S Song. The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol 2005 Oct: 7(4):452-464). http://neurooncology.mc.duke.edu;DOI:10.1215/S1152851705000232
Keywords/Mesh: cardiovascular system, vascularisation, blood vessel, mesentery, capillary, endothelium, pericyte, histology, POJA collection