Title: PAS-positively stained neutrophilic granulocytes in bone marrow smear (human)
Description: Stain: Periodic acid-Schiff reaction (PAS).
Mature neutrophils (1) have fine positive granules within negatively (un)stained cytoplasm, whereas eosinophils (2) and basophils show a positive cytoplasmic reaction contrasting with the negative granules.
In lymphocytes (3) PAS-positive granules are rare but their number increases in reactive processes, e.g. infectious mononucleosis and viral infections, and in lymphoproliferative disorders such as chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma.
Keywords/Mesh: blood, bone marrow, PAS reaction, granulocyte, histology, POJA collection