9.7 POJA-L2994+2993
+2992.
Neuroendocrine bodies (II) in the principal bronchus of the golden hamster lung
9.7 POJA-L2994+2993+2992
Title: Neuroendocrine bodies (II) in the principal bronchus of the golden hamster lung
Description:
Bronchus, electron microscopy. The neuroepithelial bodies are often arranged around a capillary (A, 1).
These pulmonary neuroendocrine cells (PNEC) are specialized solitary epithelial cells sometimes arranged in clusters called neuroepithelial bodies (NEB) in the lung. These bodies appear as oygen-sensitive chemoreceptors.
Several cells in (A) contain small dark granules with hormones which are secreted laterally and basically towards capillaries (1).
(2) Neuroendocrine cell with granules, these so-called Kultschitsky type cells are also found within the lining respiratory mucosa,
they are classified as APUD cells (Amine Precursor Uptake Decarboxylation).
Cross-sections of mitochondria clusters in non-myelinated cholinergic axon endings in (B, 4).
(B, 5) Neuroendocrine cell with adrenalin-like granules. (B, 7) Ciliated cells facing lumen of the bronchus.
(C, 6) Lysosomal structure (lipofuscin-like).
Pulmonary neuroepithelial bodies (NEBs) are densely innervated groups of neuroendocrine cells (A, 2 - B, 5 - C) invariably accompanied
by Clara-like cells (secreting cells of the lining epithelial of a bronchus).
Excitation of the NEBs provoked release of catecholamines and polypeptide hormones that act on the smooth muscle cells of the airway, e.g. hypoxia can induce the secretion of serotonin from NEB’s.
Keywords/Mesh: lung, bronchus, neuroendocrine body, neuroendocrine cell, APUD cell, chemoreceptor, histology, electron microscopy, POJA collection
Title: Neuroendocrine bodies (II) in the principal bronchus of the golden hamster lung
Description:
Bronchus, electron microscopy. The neuroepithelial bodies are often arranged around a capillary (A, 1).
These pulmonary neuroendocrine cells (PNEC) are specialized solitary epithelial cells sometimes arranged in clusters called neuroepithelial bodies (NEB) in the lung. These bodies appear as oygen-sensitive chemoreceptors.
Several cells in (A) contain small dark granules with hormones which are secreted laterally and basically towards capillaries (1).
(2) Neuroendocrine cell with granules, these so-called Kultschitsky type cells are also found within the lining respiratory mucosa,
they are classified as APUD cells (Amine Precursor Uptake Decarboxylation).
Cross-sections of mitochondria clusters in non-myelinated cholinergic axon endings in (B, 4).
(B, 5) Neuroendocrine cell with adrenalin-like granules. (B, 7) Ciliated cells facing lumen of the bronchus.
(C, 6) Lysosomal structure (lipofuscin-like).
Pulmonary neuroepithelial bodies (NEBs) are densely innervated groups of neuroendocrine cells (A, 2 - B, 5 - C) invariably accompanied
by Clara-like cells (secreting cells of the lining epithelial of a bronchus).
Excitation of the NEBs provoked release of catecholamines and polypeptide hormones that act on the smooth muscle cells of the airway, e.g. hypoxia can induce the secretion of serotonin from NEB’s.
Keywords/Mesh: lung, bronchus, neuroendocrine body, neuroendocrine cell, APUD cell, chemoreceptor, histology, electron microscopy, POJA collection