13.1 POJA-L2380+4656+4657+La0304
Fenestrated capillaries in renal glomeruli (rat)
13.1 POJA-L2380+4656+4657+La0304
Title: Fenestrated capillaries in renal glomeruli (rat)
Description:
(A): Scanning electron micrograph of a renal glomerulus. The capillary is completely covered by countless thin processes of a visceral epithelial cell (= podocyte). (1) Podocyte that engulfs with finger-like protrusions the blood vessel. (2) Bowman’s space. (3) Filtration slits, the spaces between the secondary pedicles. (4) Primary pedicle.
(B): Electron micrograph of glomerular capillary. (3) Pedicles of the podocyte at the outside of the capillary. (5) Fenestrated endothelium without diaphragms in the capillary lumen. (6) Nucleus of the endothelial cell.
(C): Electron micrograph of a glomerular capillary. (3) Pedicles of the podocyte. (5) Fenestrated endothelium of the capillary, cut tangentially, note no diaphragms present.
(D): Electron micrograph of a detail of the basement membrane of the glomerular capillary (= GBM glomerular basement membrane), the arrows indicate the slit pores between the pedicles (3) of the podocyte (filtration). (5) Fenestrated endothelium without diaphragm. (7) Thick basement membrane of the capillary. At the right the podocyte and its nucleus.
Background: The fenestrations (or pores) in the endothelium of the capillaries can be equipped with a thin diaphragm. The pores are about 70 nm wide i.e. kidney, gastrointestinal mucosa. In the kidney the bun of capillaries (= renal glomerulus) shows fusion of the basal laminae of the endothelium and visceral epithelial cells (so-called podocytes). The result is a cluster of capillaries with continuous fused dual basal laminae (= glomerular basement membrane or GBM) and fenestrae in the endothelium however without diaphragms!
Keywords/Mesh: cardiovascular system, vascularisation, glomerulus, kidney, capillary, endothelium, fenestra, basal lamina, glomerular basement membrane, slit pore, podocyte, Bowman’s space, electron microscopy, histology, POJA collection
Title: Fenestrated capillaries in renal glomeruli (rat)
Description:
(A): Scanning electron micrograph of a renal glomerulus. The capillary is completely covered by countless thin processes of a visceral epithelial cell (= podocyte). (1) Podocyte that engulfs with finger-like protrusions the blood vessel. (2) Bowman’s space. (3) Filtration slits, the spaces between the secondary pedicles. (4) Primary pedicle.
(B): Electron micrograph of glomerular capillary. (3) Pedicles of the podocyte at the outside of the capillary. (5) Fenestrated endothelium without diaphragms in the capillary lumen. (6) Nucleus of the endothelial cell.
(C): Electron micrograph of a glomerular capillary. (3) Pedicles of the podocyte. (5) Fenestrated endothelium of the capillary, cut tangentially, note no diaphragms present.
(D): Electron micrograph of a detail of the basement membrane of the glomerular capillary (= GBM glomerular basement membrane), the arrows indicate the slit pores between the pedicles (3) of the podocyte (filtration). (5) Fenestrated endothelium without diaphragm. (7) Thick basement membrane of the capillary. At the right the podocyte and its nucleus.
Background: The fenestrations (or pores) in the endothelium of the capillaries can be equipped with a thin diaphragm. The pores are about 70 nm wide i.e. kidney, gastrointestinal mucosa. In the kidney the bun of capillaries (= renal glomerulus) shows fusion of the basal laminae of the endothelium and visceral epithelial cells (so-called podocytes). The result is a cluster of capillaries with continuous fused dual basal laminae (= glomerular basement membrane or GBM) and fenestrae in the endothelium however without diaphragms!
Keywords/Mesh: cardiovascular system, vascularisation, glomerulus, kidney, capillary, endothelium, fenestra, basal lamina, glomerular basement membrane, slit pore, podocyte, Bowman’s space, electron microscopy, histology, POJA collection