7.2 POJA-L1578+1599+1841. Survey of cervical canal (uterus, human, menopause)
7.2 POJA-L1578+1599+1841
Title: Survey of cervical canal (uterus, human, menopause)
Description: Stain: Hematoxylin-eosin.
(A): Survey of cervical canal with (1) lumen; (2) portio vaginalis or ectocervix; (3) external os; (4) nabothian cysts or nabothian follicles of varying diameter and (5) myometrium with blood vessels.
(B, C): The lumen (1) with mucus content is lined by non-keratinised stratified squamous epithelium (NKSSE) (→) of the ectocervix (portio vaginalis); (3) external os. Deep invaginations (or crypts) represent tubular cervical glands (6); (7) proper lamina and (8) is area of the endocervix. The nabothian cysts (4) at varying diameters did arise by occlusion of obliterating openings of glands and contain masses of mucus. The transformation zone (*) or squamocolumnar junction high in the cervical canal indicates that this specimen is possible postmenopausal. In older women junction may retreat into the endocervical canal.
Clinical background: After puberty the former alkaline pH of vagina and cervix becomes acidic due to glycogen breakdown (bacteria) in the NKSSE. The size of squamocolumnar junction is variable and normally it is found in the area of the external os. Upon exposure to the acidic environment squamous metaplasia is induced and new squamous epithelium is found in the transformation zone previously occupied by columnar endocervical epithelium. The consequence of squamous metaplasia is that the apertures of some deep crypts of the endocervical glands become obliterated. The mucus accumulates resulting in spherical cysts lined by flattened glandular epithelium and varying in size up to 5 mm or more in diameter.
Keywords/Mesh: female reproductive organs, ectocervix, nabothian cyst, portio vaginalis, endocervix, cervix uteri, myometrium, histology, POJA collection.
Title: Survey of cervical canal (uterus, human, menopause)
Description: Stain: Hematoxylin-eosin.
(A): Survey of cervical canal with (1) lumen; (2) portio vaginalis or ectocervix; (3) external os; (4) nabothian cysts or nabothian follicles of varying diameter and (5) myometrium with blood vessels.
(B, C): The lumen (1) with mucus content is lined by non-keratinised stratified squamous epithelium (NKSSE) (→) of the ectocervix (portio vaginalis); (3) external os. Deep invaginations (or crypts) represent tubular cervical glands (6); (7) proper lamina and (8) is area of the endocervix. The nabothian cysts (4) at varying diameters did arise by occlusion of obliterating openings of glands and contain masses of mucus. The transformation zone (*) or squamocolumnar junction high in the cervical canal indicates that this specimen is possible postmenopausal. In older women junction may retreat into the endocervical canal.
Clinical background: After puberty the former alkaline pH of vagina and cervix becomes acidic due to glycogen breakdown (bacteria) in the NKSSE. The size of squamocolumnar junction is variable and normally it is found in the area of the external os. Upon exposure to the acidic environment squamous metaplasia is induced and new squamous epithelium is found in the transformation zone previously occupied by columnar endocervical epithelium. The consequence of squamous metaplasia is that the apertures of some deep crypts of the endocervical glands become obliterated. The mucus accumulates resulting in spherical cysts lined by flattened glandular epithelium and varying in size up to 5 mm or more in diameter.
Keywords/Mesh: female reproductive organs, ectocervix, nabothian cyst, portio vaginalis, endocervix, cervix uteri, myometrium, histology, POJA collection.