7.4 POJA-L4179+4181+4182
Title: Invasive ductal mamma carcinoma, no special type (NST) (human)
Description: Stain: Hematoxylin-eosin.
(A): Survey of sheets and nests (1) of an invasive ductal carcinoma with focally luminization (2).
(B): Detail of A shows solid cell nests with tumor cells (1) varying from small cells with moderately hyperchromatic regular nuclei to lighter-stained polygonal cells with regular nuclei. Surrounding dense fibrous tissue at (2).
(C): Cords and sheets of large malignant epithelial cells (1) infiltrate in a disordered organization between bands of collagen. Tumor cells extend from the fibrous tissue into and replace adjacent adipose tissue (3). (By courtesy of F. van de Molengraft MD PhD, Department of Pathology, Rijnstate Hospital, Arnhem, The Netherlands).
Background: Invasive ductal carcinoma NST (no special type) includes the majority of invasive breast carcinoma (over 50 up to 80%). Most of these neoplasms show an increase in dense fibrous tissue stroma (scirrhous carcinoma). The tumor grows as fairly sharply delineated nodules (average 1 up to 2 cm). They may attach to their surroundings with fixation to underlying chest wall thus infiltrating elsewhere. Generally dimpled skin and retraction of the nipple occur.
Keywords/Mesh: breast, mammary glands, breast neoplasms, carcinoma, ductal, histology, POJA collection,
Title: Invasive ductal mamma carcinoma, no special type (NST) (human)
Description: Stain: Hematoxylin-eosin.
(A): Survey of sheets and nests (1) of an invasive ductal carcinoma with focally luminization (2).
(B): Detail of A shows solid cell nests with tumor cells (1) varying from small cells with moderately hyperchromatic regular nuclei to lighter-stained polygonal cells with regular nuclei. Surrounding dense fibrous tissue at (2).
(C): Cords and sheets of large malignant epithelial cells (1) infiltrate in a disordered organization between bands of collagen. Tumor cells extend from the fibrous tissue into and replace adjacent adipose tissue (3). (By courtesy of F. van de Molengraft MD PhD, Department of Pathology, Rijnstate Hospital, Arnhem, The Netherlands).
Background: Invasive ductal carcinoma NST (no special type) includes the majority of invasive breast carcinoma (over 50 up to 80%). Most of these neoplasms show an increase in dense fibrous tissue stroma (scirrhous carcinoma). The tumor grows as fairly sharply delineated nodules (average 1 up to 2 cm). They may attach to their surroundings with fixation to underlying chest wall thus infiltrating elsewhere. Generally dimpled skin and retraction of the nipple occur.
Keywords/Mesh: breast, mammary glands, breast neoplasms, carcinoma, ductal, histology, POJA collection,