4.1.1 POJA-L-3970+3973+La-0147+3990. Fundus glands of the stomach (human, dog, guinea pig)
4.1.1 POJA-L3970+3973+La-0147+3990
Title: Fundus glands of the stomach (human, dog, guinea pig)
Description: Stain: (A) Hematoxylin-eosin (human). (B) Alum hematoxylin-eosin mucocarmin (dog). (C) Alum hematoxylin-eosin azocarmin (human). (D) Electron micrograph (guinea pig).
The gastric foveolae in the fundus of the stomach (A, B) are limited with columnar epithelial cells. They are usually wider and shorter than crypts in the other parts of the intestine. The cells secrete PAS-positive mucus that protects the cells against the HCl of the parietal cells.
Between the foveolae and glands the lamina propria connective tissue (2) embeds many capillaries and cells of the immune system.
In the middle and lower part of the gastric glands (C, D) three different cell types are found:
The chief cells (4) producing pepsinogen (and some lipases), packed in electron-light granules, and rich in RER (rough endoplasmic reticulum).
The parietal or oxyntic cells (3) producing HCl (and intrinsic factor). They are equipped with a vast system of intracellular canaliculi and transport vesicles (6), as well as many large mitochondria.
The enteroendocrine cells (5, ↘↘) producing several types of hormones (gastrin, glucagon) involved in the regulation of HCL and pepsinogen production. These latter cells pack their products in small electron dense granules located predominantly at the basal side of the cell, nearby the capillaries.
Keywords/Mesh: stomach, foveolae, parietal cells, chief cells, enteroendocrine cells, neck cells, electron microscopy
Title: Fundus glands of the stomach (human, dog, guinea pig)
Description: Stain: (A) Hematoxylin-eosin (human). (B) Alum hematoxylin-eosin mucocarmin (dog). (C) Alum hematoxylin-eosin azocarmin (human). (D) Electron micrograph (guinea pig).
The gastric foveolae in the fundus of the stomach (A, B) are limited with columnar epithelial cells. They are usually wider and shorter than crypts in the other parts of the intestine. The cells secrete PAS-positive mucus that protects the cells against the HCl of the parietal cells.
Between the foveolae and glands the lamina propria connective tissue (2) embeds many capillaries and cells of the immune system.
In the middle and lower part of the gastric glands (C, D) three different cell types are found:
The chief cells (4) producing pepsinogen (and some lipases), packed in electron-light granules, and rich in RER (rough endoplasmic reticulum).
The parietal or oxyntic cells (3) producing HCl (and intrinsic factor). They are equipped with a vast system of intracellular canaliculi and transport vesicles (6), as well as many large mitochondria.
The enteroendocrine cells (5, ↘↘) producing several types of hormones (gastrin, glucagon) involved in the regulation of HCL and pepsinogen production. These latter cells pack their products in small electron dense granules located predominantly at the basal side of the cell, nearby the capillaries.
Keywords/Mesh: stomach, foveolae, parietal cells, chief cells, enteroendocrine cells, neck cells, electron microscopy