2.2 POJA-L1116. The effect of cyclophosphamide treatment on the B and T cells in the spleen (rat)
2.2 POJA-L1116
Title: The effect of cyclophosphamide treatment on the B and T cells in the spleen (rat)
Description: Stain: Immunoperoxidase-DAB staining with antibodies to B cells (mark-1), CD3 and CD8 T cells.
(A): B cells in the follicles, germinal centres (2) and corona are stained positive brown, while the PALS area (1) is negative (blue).
(B): About half of the lymphocytes in the PALS area (1) are stained brown positively. The B cell areas (2) are negative (blue).
(C): About half of the lymphocytes in the PALS area (1) are stained positively, while the B cell area (2) remains unstained.
Both B cells and T cells are reduced 4-8 days after the cyclophosphamide treatment.
Cyclophosphamide causes temporarily severe immunosupression.
Keywords/Mesh: lymphatic organ, spleen, T cells, B cells, CD8, CD3, Cyclophosphamide, histology, POJA collection
Title: The effect of cyclophosphamide treatment on the B and T cells in the spleen (rat)
Description: Stain: Immunoperoxidase-DAB staining with antibodies to B cells (mark-1), CD3 and CD8 T cells.
(A): B cells in the follicles, germinal centres (2) and corona are stained positive brown, while the PALS area (1) is negative (blue).
(B): About half of the lymphocytes in the PALS area (1) are stained brown positively. The B cell areas (2) are negative (blue).
(C): About half of the lymphocytes in the PALS area (1) are stained positively, while the B cell area (2) remains unstained.
Both B cells and T cells are reduced 4-8 days after the cyclophosphamide treatment.
Cyclophosphamide causes temporarily severe immunosupression.
Keywords/Mesh: lymphatic organ, spleen, T cells, B cells, CD8, CD3, Cyclophosphamide, histology, POJA collection