2.0 LYMPHATIC ORGANS: INTRODUCTION
The lymphatic organs serve the immune response carried out by T cells, B cells, dendritic cells, macrophages, granulocytes as well as by products derived from these cells. The following organs are included:
2.1 - images: Thymus gland
T cells originate from precursosr cells in the bone marrow, migrate to the thymus where they divide and mature into immunocompetent T cells that subsequently leave the thymus and become operational in the other lymphatic organs and in blood. The maturation of T cells is triggered by dendritic cell types.
See: 2.1 POJA-L-900
2.2 - images: Spleen
The spleen is the place where T-, B- and antigen presenting cells cooperate to mount an immune response. The spleen also removes unwanted material and aged erythrocytes by phagocytosis in the red pulp area. The spleen is equiped with sinusoids. The white pulp is the area with a dense population of lymphoid cells (lymph follicles and periarteriolar lymphocyte sheaths (PALS). B- and T cell areas are visualised with specific antibodies.
See: 2.1 POJA-L922 and 2.2 POJA-L1092
2.3 - images: Lymph nodes
Similar functions are also carried out by lymph nodes positioned in the chain of lymphatic vessels draining anatomical regions.
See: 2.3 POJA-L1094
2.4 - images: Mucosa-associated lymphoid tissue or MALT
Lymphoid tissue is also located and associated with mucosa (MALT) of the gastrointestinal, respiratory and urogenital tracts to protect specifically against local invasions.
The lymphatic organs serve the immune response carried out by T cells, B cells, dendritic cells, macrophages, granulocytes as well as by products derived from these cells. The following organs are included:
2.1 - images: Thymus gland
T cells originate from precursosr cells in the bone marrow, migrate to the thymus where they divide and mature into immunocompetent T cells that subsequently leave the thymus and become operational in the other lymphatic organs and in blood. The maturation of T cells is triggered by dendritic cell types.
See: 2.1 POJA-L-900
2.2 - images: Spleen
The spleen is the place where T-, B- and antigen presenting cells cooperate to mount an immune response. The spleen also removes unwanted material and aged erythrocytes by phagocytosis in the red pulp area. The spleen is equiped with sinusoids. The white pulp is the area with a dense population of lymphoid cells (lymph follicles and periarteriolar lymphocyte sheaths (PALS). B- and T cell areas are visualised with specific antibodies.
See: 2.1 POJA-L922 and 2.2 POJA-L1092
2.3 - images: Lymph nodes
Similar functions are also carried out by lymph nodes positioned in the chain of lymphatic vessels draining anatomical regions.
See: 2.3 POJA-L1094
2.4 - images: Mucosa-associated lymphoid tissue or MALT
Lymphoid tissue is also located and associated with mucosa (MALT) of the gastrointestinal, respiratory and urogenital tracts to protect specifically against local invasions.
- GALT (gut-associated lymphoid tissue): Tonsils, Peyer's patches. See: 2.4 POJA-L1100 and 2.4-POJA-L1101
- BALT (Bronchus-associated lymphoid tissue). See: 8.3 POJA-L337
- Others
COPYRIGHTS
All rights reserves worldwide for the POJA collection are hold by L.G. Poels and P.H.K. Jap and Radboud University Medical Center (Radboud UMC Nijmegen). No one may modify, copy, distribute, transmit, display, or publish any materials contained in the POJA collection without prior written permission of the authors Poels and Jap or the UMC St Radboud. Any commercial use of the POJA collection is forbidden. POJA images are partly deposited in the Health Education Assets Library (HEAL database) as well as in the MedEdPortal/AAMC database).
All rights reserves worldwide for the POJA collection are hold by L.G. Poels and P.H.K. Jap and Radboud University Medical Center (Radboud UMC Nijmegen). No one may modify, copy, distribute, transmit, display, or publish any materials contained in the POJA collection without prior written permission of the authors Poels and Jap or the UMC St Radboud. Any commercial use of the POJA collection is forbidden. POJA images are partly deposited in the Health Education Assets Library (HEAL database) as well as in the MedEdPortal/AAMC database).