1.1 POJA-L564+565-HV. Leukocyte Alkaline Phosphatase (LAP/NAP score) in peripheral blood smear (human)

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1.1  POJA-L564+565-HV

Title: Leukocyte Alkaline Phosphatase (LAP/NAP score) in peripheral blood smear (human)
                                                                      
Description: Stain: Alkaline phosphatase staining (Ackerman).

​ In mature neutrophils granules contain alkaline phosphatase. In eosinophils no alkaline phosphatase activity is present.  
​A considerable number of brown stained neutrophils can be indicative for a patient with infection (leukemoid reaction, A).

Image in (B) is from a patient with CML (chronic myeloid leukaemia) showing an increased number of leucocytes without toxic granules, i.e.  alkaline phosphatase-negative.

Cytochemical reactions in smears are useful for the differential diagnosis of certain diseases.
  
Keywords/Mesh: blood, bone marrow, alkaline leukocyte phosphatase, neutrophil, LAP score, leukemoid reaction, chronic myeloid leukemia, histology, POJA collection