Title: Fibrillin in the alveoli in lung tissue
Imunoperoxidase staining with anti-fibrillin antibodies and diaminobenzidin reaction (frozen section), adult human. Fibrillin
is one of the elastin-associated microfibrillar proteins that enwraps the elastin protein core and is localized in normal lung structures such as alveolar septa and tips. The immuno-staining reveals the thread-like black fibrillin deposits. (A) are the alveolar spaces, and arrowheads point to alveolar tips (↓1), where coiled deposits can be discerned. Open capillaries are indicated by (2↓)
Title: Fibrillin in the alveoli of the lung
Anti-fibrillin antibody immunoperoxidase staining with diaminobenzidin reaction, adult human. Fibrillin is one of the elastin-associated microfibrillar proteins. Here fibrillin (and elastin) is localized as brown threads in the alveolar septa and alveolar tips (1). The elastin is visible as white threads (2).
Title: Detail of elastin in an alveolar tip
Electron microscopy, adult human. Note the lace-like pattern of lumps of amorph elastin (X) that appears more electron-dense than the collagen fibers (C). At this high magnification cross-sectioned microfibrils (that contain among others fibrillin) are present in close association (*) with different areas of elastin. (1) Indicate extensions of elastoblast (or interstitial myofibroblast).
Keywords/Mesh: respiratory system, lung, alveolus, alveolar tip,
myofibroblast, elastoblast, collagen, elastin, microfibril, fibrillin,
elastin-associated protein, histology, electron microscopy, POJA collection