4.2.1 POJA-L3797+3798+3800+3801+3799
Title: Examples cellular pathology of steatosis in liver (human)
Description: Stain: (A, B) Hematoxylin-eosin. (C, D, E) Electron micrographs.
(A) Chronic aggressive hepatosteatosis or steatohepatitis preferentially in the periportal area. It is intracytoplasmic accumulation of triglycerides, initially as small fat vacuoles around the nucleus. In later stages the fat vacuoles increase in size pushing the nucleus aside (fatty liver).
(B) Periportal macrovacuolar steatosis, the fat droplets are stored in a single large vesicle occupying nearly the whole cell.
(C, D) Large fat vacuole near the nucleus in case of alcoholic hepatitis.
(E) Steatosis developed during rheumatoid arthritis. Two types of steatosis are usually discerned: Macrovesicular type due to oversupply of lipids (alcoholism) and the microvesicular fatty degeneration characterized by small intracytoplasmic fat vacuoles (Tetracycline’s, acute fatty liver of Pregnancy, Rey’s syndrome, and Hepatitis D).
Keywords/Mesh: liver, hepatosteatosis, steatohepatitis, electron microscopy, histology, POJA collection
Title: Examples cellular pathology of steatosis in liver (human)
Description: Stain: (A, B) Hematoxylin-eosin. (C, D, E) Electron micrographs.
(A) Chronic aggressive hepatosteatosis or steatohepatitis preferentially in the periportal area. It is intracytoplasmic accumulation of triglycerides, initially as small fat vacuoles around the nucleus. In later stages the fat vacuoles increase in size pushing the nucleus aside (fatty liver).
(B) Periportal macrovacuolar steatosis, the fat droplets are stored in a single large vesicle occupying nearly the whole cell.
(C, D) Large fat vacuole near the nucleus in case of alcoholic hepatitis.
(E) Steatosis developed during rheumatoid arthritis. Two types of steatosis are usually discerned: Macrovesicular type due to oversupply of lipids (alcoholism) and the microvesicular fatty degeneration characterized by small intracytoplasmic fat vacuoles (Tetracycline’s, acute fatty liver of Pregnancy, Rey’s syndrome, and Hepatitis D).
Keywords/Mesh: liver, hepatosteatosis, steatohepatitis, electron microscopy, histology, POJA collection