10.7 POJA-L4341+2016+3888+4344+4346
Title: Verruca vulgaris (common wart, viral infection) I
Description:
Common wart (viral infection), stain hematoxylin-eosin, human.
(A): Normal epidermis/dermis close to the wart area. Note slight keratinisation of epidermis. Hair follicles with sebaceous glands.
(B): Papillomatous epidermal hyperplasia. The thickened epidermis thrown into papillary folds and the rete ridges are elongated.
(C): Hyperkeratosis (1) alternates with parakeratosis (2).
(D): Parakeratosis.
(F): In human papillomavirus (HPV)-infected cells the keratins show angular aggregates (arrow).
The vacuolated cytoplasm has eosinophilic inclusions. Some cells contain large clumped keratohyalin granules
(Micrographs (C, F) by courtesy of D. Ruiter, MD PhD, former Head Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands)
Background: Verrucae are common lesions at any age and are caused by a DNA virus i.e. HPV. Generally they are self-limited and will regress spontaneously within months to few years. The common warts can occur anywhere, most frequently on the hands as gray-white papules with a rough surface.
Keywords/Mesh: skin, verruca vulgaris, wart, HPV infection, histology, pathology, POJA collection
Title: Verruca vulgaris (common wart, viral infection) I
Description:
Common wart (viral infection), stain hematoxylin-eosin, human.
(A): Normal epidermis/dermis close to the wart area. Note slight keratinisation of epidermis. Hair follicles with sebaceous glands.
(B): Papillomatous epidermal hyperplasia. The thickened epidermis thrown into papillary folds and the rete ridges are elongated.
(C): Hyperkeratosis (1) alternates with parakeratosis (2).
(D): Parakeratosis.
(F): In human papillomavirus (HPV)-infected cells the keratins show angular aggregates (arrow).
The vacuolated cytoplasm has eosinophilic inclusions. Some cells contain large clumped keratohyalin granules
(Micrographs (C, F) by courtesy of D. Ruiter, MD PhD, former Head Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands)
Background: Verrucae are common lesions at any age and are caused by a DNA virus i.e. HPV. Generally they are self-limited and will regress spontaneously within months to few years. The common warts can occur anywhere, most frequently on the hands as gray-white papules with a rough surface.
Keywords/Mesh: skin, verruca vulgaris, wart, HPV infection, histology, pathology, POJA collection