7.4 POJA-L-194+201
Title: Normal breast in pregnancy and in premenopause (human).
Description: Stain: (A) Azan; (B) Hematoxylin-eosin.
(A): Early pregnancy. Survey of enlarged lobules (1) and extralobular terminal ducts (2). Several lobules contain dilated alveoli (or acini) (**). Blue-stained extralobular fibrocollagenous tissue (3) and adipose tissue (4).
(B): Premenopausal breast. Survey of small atrophied lobules (1) with more shrinkage of intralobular and interlobular stroma. Extralobular terminal ducts (2) are dilated. Thicker dense fibrocollagenous tissue (3) and increased amounts of adipose tissue (4).
Background: The stroma forms the connective tissue framework supporting the epithelial parenchyma (lobules, ducts and alveoli) and comprises fibroblasts, macrophages, endothelial cells and adipocytes and are collectively referred to as the mammary fat pad (Neville et al. 1998). In breast tissue of young women the interlobular stroma is radio-dense and with aging it is progressively replaced by radiolucent adipose tissue. There is almost no adipose tissue in most breast tumors and mammographically tumors appear as denser masses in contrast to the surrounding breast stroma in the elderly. In younger women mammography is less sensitive because such dense masses might be obscured by surrounding radio-dense interlobular stroma.
Keyword(s)/Mesh: Breast, mammary glands, lactation, histology, pregnancy, POJA collection, female organs.
Title: Normal breast in pregnancy and in premenopause (human).
Description: Stain: (A) Azan; (B) Hematoxylin-eosin.
(A): Early pregnancy. Survey of enlarged lobules (1) and extralobular terminal ducts (2). Several lobules contain dilated alveoli (or acini) (**). Blue-stained extralobular fibrocollagenous tissue (3) and adipose tissue (4).
(B): Premenopausal breast. Survey of small atrophied lobules (1) with more shrinkage of intralobular and interlobular stroma. Extralobular terminal ducts (2) are dilated. Thicker dense fibrocollagenous tissue (3) and increased amounts of adipose tissue (4).
Background: The stroma forms the connective tissue framework supporting the epithelial parenchyma (lobules, ducts and alveoli) and comprises fibroblasts, macrophages, endothelial cells and adipocytes and are collectively referred to as the mammary fat pad (Neville et al. 1998). In breast tissue of young women the interlobular stroma is radio-dense and with aging it is progressively replaced by radiolucent adipose tissue. There is almost no adipose tissue in most breast tumors and mammographically tumors appear as denser masses in contrast to the surrounding breast stroma in the elderly. In younger women mammography is less sensitive because such dense masses might be obscured by surrounding radio-dense interlobular stroma.
Keyword(s)/Mesh: Breast, mammary glands, lactation, histology, pregnancy, POJA collection, female organs.